Metastasis-Directed Therapy for Genitourinary Malignancies: Progress and Potential

Matthew Deek, MD, of the Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, provides an overview of the concept of metastasis-directed therapy, the current research in specific genitourinary malignancies where metastasis-directed therapies have shown promise, and how metastasis-directed therapies relate to toxicities and patient-reported outcomes to date.

Dr. Deek begins by explaining how metastasis-directed therapy differs from traditional cancer treatments. He also gives a brief explanation of the spectrum theory of metastasis and the ways in which it has shaped how local therapies are being evaluated to treat metastatic disease.

He concludes with a note on the future of metastasis-directed therapy, including the other genitourinary settings in which this therapy is being investigated.