Survival Outcomes Data From Neoadjuvant Chemotherapy and Surgical Consolidation in cN+ UTUC

Joon Kyung Kim, MD, of the University of Kentucky, discusses the findings from a retrospective analysis evaluating systemic therapy and surgical consolidation in patients with node-positive upper tract urothelial carcinoma. With limited level-one data guiding treatment decisions for this aggressive disease, this study explores the role of neoadjuvant and adjuvant chemotherapy as well as the impact of surgical intervention. Dr. Kim highlights the unique challenges of treating upper tract disease, which has historically been managed by extrapolating data from muscle-invasive bladder cancer trials. The discussion covers key findings suggesting that surgical consolidation may be an important component of treatment.