In part two of the Radioligands session from Uromigos Live 2024, moderator Brian Rini, MD, leads a discussion on the key findings from the SPLASH trial presented at ESMO, focusing on the effects of dosing in PSMA-targeted radioligand therapy. Dr. Rini is joined by a panel consisting of Karen Autio, MD; Michael Morris, MD; Gary T. Smith, MD; and Tanya Dorff, MD, to highlight differences in outcomes such as radiographic progression-free survival and overall survival compared to previous trials, including the role of dose adjustments.