At Uromigos Live 2024, a panel moderated by Tom Powles focused on IO rechallenge in renal cell carcinoma, featuring discussion on new trial data and more. The panel included Brian Rini, along with Tian Zhang, MD, UT Southwestern Medical Center; Toni Choueiri, MD, Dana-Farber Cancer Center; and David McDermott, MD, Beth Israel Deaconess Medical Center.
In part one of the session, the panelists discuss the use of immune checkpoint inhibitors, specifically focusing on the considerations around re-challenging patients with PD-1/PD-L1 therapies after disease progression. The conversation addresses the effectiveness of re-administering treatments like nivolumab and pembrolizumab, particularly in metastatic settings.
Uromigos Live 2024 RCC IO Rechallenge Part 1: CONTACT-03, TiNivo-2 Study Results and Implications
By Thomas Powles, MBBS, MRCP, MD, Brian Rini, MD, FASCO, Tian Zhang, MD, Toni Choueiri, MD, David F. McDermott, MD - Last Updated: October 29, 2024Related Posts
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Patients with mRCC on Medicare have better survival rates compared with patients on Medicaid or with no insurance.
A recent proof-of-concept study has further evaluated the efficacy of PSMA-guided MDT for oligometastatic RCC.
The panel concludes with future directions in RCC, including HIF inhibitors and biomarker-guided adjuvant strategies.
The panel considers how managing real-world patients on novel therapies like belzutifan presents a multitude of challenges.
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